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KMID : 0604520050310020189
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Journal of the Society of Cosmetic Scientists of Korea
2005 Volume.31 No. 2 p.189 ~ p.196
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Study of Antioxidation Action of Lenonuri herba Extract
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Kim Ji-Young
No Bo-Kyung
Lee Yeon-Hee
Kim Ju-Youn
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Abstract
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Motherwort (Leonurus sibiricus L), a hemp nettle (Labiatae) plant, grows about 1.5{~}2 m high spontaneously to wildness in Korea, China, Japan, and other Asian place. Its medical applications includes women’’s uterine disease, urination, bloody stool, bloody urine, and hemorrhoids. It’’s also effective for high blood pressure, heart stimulation, and anti-cancer activity. We first prepared chlroform and methanol extracts of motherwort and then they were fractionated using water, 30% methanol, 60% methanol, and 100% methanol, respectively. Each fractionates is assayed for free radical scavenging activities against DPPH and anti-oxidant activity by TBARS assay measuring lipid peroxidation using LDL. The 30% and 60% methanol fractionates of methanol extracts showed strong anti-oxidant activity compared to vitamin C. They also had more Potent SOD activity using pyrogallol at 250 ppm than that of vitamin C. These results suggest that anti-oxidant activities of motherwort may be applicable to development of natural anti-oxidant cosmetics. Possibility of nature anti-oxidation ability cosmetics is seen possibility low official.
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KEYWORD
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DPPH, scavenging activity, LDL lipidperoxidation, TBARS assay
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